Colchicine bertindak dengan menghalang penghijrahan sel darah putih (neutrofil) ke kawasan yang terjejas. Ini ibarat menghentikan kemasukan pasukan bomba yang tidak diperlukan ke kawasan kebakaran kecil—keradangan akan berkurang, dan kesakitan beransur-ansur reda.
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Colchicine boleh diekskresikan ke dalam susu ibu. Namun, jumlah yang dipindahkan adalah kecil, dan kesannya terhadap bayi biasanya tidak signifikan. Walaupun begitu:
Ubat yang digunakan untuk merawat serangan gout akut pada masa yang sama mencegah serangan berikutnya. Ia tidak berkesan untuk menyembuhkan gout atau menurunkan kadar asid urik. Ditetapkan untuk mencegah atau melegakan bengkak gout dengan mengurangkan keradangan.
Baking soda mempu mengurangkan asid urik dalam badan dan mengurangkan keradangan akibat gout. Caranya:
Talk to your physician regarding the greatest medicines to suit your needs. The kind will count on how well your kidneys operate, the feasible Unintended effects, and other medical issues.
Probenecid is minimally successful, so look at switching to febuxostat in place of including probenecid for poor Regulate on the very best tolerated dose of allopurinol.
Gout is easily diagnosed and managed with low-priced, readily available medicines but has traditionally not been given as much notice as other sorts of arthritis.
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Ample and effectively-managed reports have failed to reveal a chance to your fetus in the main trimester of pregnancy (and there is no proof of hazard in afterwards trimesters).
Serangan gout dapat terjadi dengan cepat dan terus berulang dari masa ke masa, perlahan-lahan merosakkan tisu di kawasan keradangan dan boleh menjadi sangat menyakitkan. Hipertensi, kardiovaskular website dan obesiti adalah faktor risiko bagi penyakit gout.
RELATED: Wherever to turn for agony aid - acetaminophen or NSAIDs? Uric acid-reducing medicines The ACR pointers advocate treating gout with uric acid-lowering medications for people who have tophi (nodules that form from the mass of uric acid crystals at joints or in comfortable tissues), radiographic proof (X-ray or other imaging) of harm due to gout, kidney stones (people with gout have an increased threat of kidney stones as uric acid crystals can sort kidney stones in a number of people) or two or maybe more gout get more info flares each year.